APA
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Borkar, D. S., Tabano, D., Ali, F. S., Leng, T., Garmo, V., Ahmed, A., … Singh, R. P. (2025). Early Outcomes After Initiation of Faricimab in Patients With Diabetic Macular Edema. Ophthalmic Surgery Lasers and Imaging Retina.
Chicago/Turabian
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Borkar, Durga S., David Tabano, Ferhina S Ali, Theodore Leng, Vincent Garmo, Ayesha Ahmed, Rachel Myers, Jacqueline K. Shaia, Giulio Barteselli, and Rishi P. Singh. “Early Outcomes After Initiation of Faricimab in Patients With Diabetic Macular Edema.” Ophthalmic Surgery Lasers and Imaging Retina (2025).
MLA
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Borkar, Durga S., et al. “Early Outcomes After Initiation of Faricimab in Patients With Diabetic Macular Edema.” Ophthalmic Surgery Lasers and Imaging Retina, 2025.
BibTeX Click to copy
@article{durga2025a,
title = {Early Outcomes After Initiation of Faricimab in Patients With Diabetic Macular Edema.},
year = {2025},
journal = {Ophthalmic Surgery Lasers and Imaging Retina},
author = {Borkar, Durga S. and Tabano, David and Ali, Ferhina S and Leng, Theodore and Garmo, Vincent and Ahmed, Ayesha and Myers, Rachel and Shaia, Jacqueline K. and Barteselli, Giulio and Singh, Rishi P.}
}
BACKGROUND AND OBJECTIVE This study evaluated treatment patterns and outcomes among patients with diabetic macular edema (DME) treated with the bispecific antibody faricimab in routine clinical practice in the United States.
PATIENTS AND METHODS FARETINA-DME was a retrospective study among patients with DME initiating faricimab from February 2022 to June 2023 identified from the United States IRIS® Registry.
RESULTS Four thousand five hundred fourteen (4,514) patients (6,204 eyes) previously treated with anti-vascular endothelial growth factor (anti-VEGF) therapy and 691 treatment-naïve patients (851 eyes) were included. In previously treated eyes, mean ± SD visual acuity was 64.0 ± 18.3 letters at index and 65.3 ± 19.0 at faricimab injection 4. In treatment-naïve eyes, visual acuity improved from 60.3 ± 19.8 to 63.9 ± 18.5 letters (P < 0.01). Mean ± SD central subfield thickness improved from 364.3 ± 132.2 to 330.1 ± 121.2 μm in previously treated eyes and 359.6 ± 115.0 to 307.4 ± 114.6 μm in treatment-naïve eyes (both P < 0.01).
CONCLUSIONS In patients with DME receiving faricimab, visual acuity was maintained in previously treated and improved in treatment-naïve eyes. Both groups had anatomical improvement. [Ophthalmic Surg Lasers Imaging Retina 2025;56:XX-XX.].